First Article Published! [Short Toxin-like Proteins Attack!]

SLAM: debunk creationism, pseudoscience, and superstitions. Discuss logic and morality.

Moderator: Alyrium Denryle

Post Reply
User avatar
The Grim Squeaker
Emperor's Hand
Posts: 10315
Joined: 2005-06-01 01:44am
Location: A different time-space Continuum
Contact:

First Article Published! [Short Toxin-like Proteins Attack!]

Post by The Grim Squeaker »

I just realized I hadn't bragged about this, yet, (here) -
The first article I was involved in got published. Yay! :)
(I'm a minor co-contributor, but it still counts ^_^. Now I await the first round of peer reviews on my real "baby" (an article where i'm the first author), but that's still in the hands of the fickle gods of acceptance and editing).

http://www.mdpi.com/2072-6651/5/7/1314

"Short Toxin-like Proteins Attack the Defense Line of Innate Immunity"
ToLIPS are pretty dang interesting BTW :).
Short Toxin-like Proteins Attack the Defense Line of Innate Immunity
Yitshak Tirosh, Dan Ofer, Tsiona Eliyahu and Michal Linial
Department of Biological Chemistry, Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem 91904, Israel
Toxins 2013, 5(7), 1314-1331; doi:10.3390/toxins5071314
Published: 23 July 2013
(This article belongs to the Special Issue Novel Properties of Well-Characterized Toxins)

Abstract:
ClanTox (classifier of animal toxins) was developed for identifying toxin-like candidates from complete proteomes. Searching mammalian proteomes for short toxin-like proteins (coined TOLIPs) revealed a number of overlooked secreted short proteins with an abundance of cysteines throughout their sequences.
We applied bioinformatics and data-mining methods to infer the function of several top predicted candidates.

We focused on cysteine-rich peptides that adopt the fold of the three-finger proteins (TFPs). We identified a cluster of duplicated genes that share a structural similarity with elapid neurotoxins, such as α-bungarotoxin. In the murine proteome, there are about 60 such proteins that belong to the Ly6/uPAR family. These proteins are secreted or anchored to the cell membrane. Ly6/uPAR proteins are associated with a rich repertoire of functions, including binding to receptors and adhesion. Ly6/uPAR proteins modulate cell signaling in the context of brain functions and cells of the innate immune system. We postulate that TOLIPs, as modulators of cell signaling, may be associated with pathologies and cellular imbalance. We show that proteins of the Ly6/uPAR family are associated with cancer diagnosis and malfunction of the immune system.
It's an open access journal for anyone who wants to read it.
http://www.mdpi.com/2072-6651/5/7/1314/pdf
Photography
Genius is always allowed some leeway, once the hammer has been pried from its hands and the blood has been cleaned up.
To improve is to change; to be perfect is to change often.
User avatar
Ziggy Stardust
Sith Devotee
Posts: 3114
Joined: 2006-09-10 10:16pm
Location: Research Triangle, NC

Re: First Article Published! [Short Toxin-like Proteins Atta

Post by Ziggy Stardust »

Congratulations! My first paper was accepted recently, but I am waiting for it to be published before bragging about it, heh.
User avatar
The Grim Squeaker
Emperor's Hand
Posts: 10315
Joined: 2005-06-01 01:44am
Location: A different time-space Continuum
Contact:

Re: First Article Published! [Short Toxin-like Proteins Atta

Post by The Grim Squeaker »

Ziggy Stardust wrote:Congratulations! My first paper was accepted recently, but I am waiting for it to be published before bragging about it, heh.
Thanks!
(And this has been published :). )
Photography
Genius is always allowed some leeway, once the hammer has been pried from its hands and the blood has been cleaned up.
To improve is to change; to be perfect is to change often.
Dr. Trainwreck
Jedi Knight
Posts: 834
Joined: 2012-06-07 04:24pm

Re: First Article Published! [Short Toxin-like Proteins Atta

Post by Dr. Trainwreck »

Congrats. You're not one of the four mentioned under the title, are you?
Ποταμοῖσι τοῖσιν αὐτοῖσιν ἐμϐαίνουσιν, ἕτερα καὶ ἕτερα ὕδατα ἐπιρρεῖ. Δὶς ἐς τὸν αὐτὸν ποταμὸν οὐκ ἂν ἐμβαίης.

The seller was a Filipino called Dr. Wilson Lim, a self-declared friend of the M.I.L.F. -Grumman
User avatar
The Grim Squeaker
Emperor's Hand
Posts: 10315
Joined: 2005-06-01 01:44am
Location: A different time-space Continuum
Contact:

Re: First Article Published! [Short Toxin-like Proteins Atta

Post by The Grim Squeaker »

Dr. Trainwreck wrote:Congrats. You're not one of the four mentioned under the title, are you?
I am :P .
If I wasn't, then I wouldn't be published now, would I? :wink:
Photography
Genius is always allowed some leeway, once the hammer has been pried from its hands and the blood has been cleaned up.
To improve is to change; to be perfect is to change often.
User avatar
Magis
Padawan Learner
Posts: 226
Joined: 2010-06-17 02:50pm

Re: First Article Published! [Short Toxin-like Proteins Atta

Post by Magis »

The downside is that since the journal now knows all your contact information, you'll probably inundated with requests to review other papers.

Anyway, congrats on the paper. Hopefully as you publish more you won't become too cynical, bitter and jaded about the entire publication process like so many people do. :)
User avatar
The Grim Squeaker
Emperor's Hand
Posts: 10315
Joined: 2005-06-01 01:44am
Location: A different time-space Continuum
Contact:

Re: First Article Published! [Short Toxin-like Proteins Atta

Post by The Grim Squeaker »

Magis wrote:
Anyway, congrats on the paper. Hopefully as you publish more you won't become too cynical, bitter and jaded about the entire publication process like so many people do. :)
So far, i'm getting lots of "Submit here" spam from no name journals :P
Photography
Genius is always allowed some leeway, once the hammer has been pried from its hands and the blood has been cleaned up.
To improve is to change; to be perfect is to change often.
User avatar
PainRack
Emperor's Hand
Posts: 7581
Joined: 2002-07-07 03:03am
Location: Singapura

Re: First Article Published! [Short Toxin-like Proteins Atta

Post by PainRack »

Congrats!

So, is it true that those who get published became the targets of metaphorical knives in the dark by other jealous peers?:D:D:D
Let him land on any Lyran world to taste firsthand the wrath of peace loving people thwarted by the myopic greed of a few miserly old farts- Katrina Steiner
User avatar
The Grim Squeaker
Emperor's Hand
Posts: 10315
Joined: 2005-06-01 01:44am
Location: A different time-space Continuum
Contact:

Re: First Article Published! [Short Toxin-like Proteins Atta

Post by The Grim Squeaker »

PainRack wrote:Congrats!

So, is it true that those who get published became the targets of metaphorical knives in the dark by other jealous peers?:D:D:D
Well, the rest of the lab has publications in nature/science, or is on the way abroad for a phd in the ivy, so, I doubt it :P.
I'm the young undergrad ;). (Well, graduate now)
Photography
Genius is always allowed some leeway, once the hammer has been pried from its hands and the blood has been cleaned up.
To improve is to change; to be perfect is to change often.
User avatar
Lagmonster
Master Control Program
Master Control Program
Posts: 7719
Joined: 2002-07-04 09:53am
Location: Ottawa, Canada

Re: First Article Published! [Short Toxin-like Proteins Atta

Post by Lagmonster »

Well done! You're officially RL leet.
Note: I'm semi-retired from the board, so if you need something, please be patient.
Post Reply