Canadian Clinic to Try Prescribing Heroin

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dr. what
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Canadian Clinic to Try Prescribing Heroin

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VANCOUVER, British Columbia - A clinic providing free heroin to Vancouver addicts is to open later this month to see if prescribing the drug can help addicts who have failed in other treatment programs.

Similar projects have been scorned in the United States, seen as unethical or dangerous. There have been such studies in the Netherlands, Switzerland, Germany and Spain.

The 12-15 month trial is to determine if prescribed, pharmaceutical-grade heroin — in conjunction with methadone treatment — is more effective than methadone alone in treating certain opiate-addicted people.

"We're trying to figure out whether we can reach out to those people with medically prescribed heroin," said Dr. Martin Schechter, principal investigator for The North American Opiate Medication Initiative.

The project also will be conducted in Toronto and Montreal, but is set to get under way in Vancouver first, following government approval — expected in about two weeks.

More than 4,000 drug addicts live near the clinic in Vancouver's impoverished Downtown Eastside, an area known for its street drug deals.

Schechter said the trial will not attract addicts from other areas because the 157 people selected to take part must have been addicted for at least five years.

Those in the project will go to the clinic three times a day. Nurses will supervise the injections. Seventy people will receive methadone; the rest will get heroin and methadone.

Some in the latter group will be given the heroin substitute hydromorphone. It is distinguishable from heroin so researchers can determine through urine analysis what percentage of participants are cheating by also using illegal heroin and thus skewing the results.

Participants will be monitored for a year after the trial to see if they relapse.

The project has scientific approval — and $6.4 million — from the Canadian Institutes of Health Research, a government agency, and the support of the University of British Columbia, the University of Toronto and the Universite de Montreal.

Several American cities had been considered for the project, but the idea was abandoned, Schechter said.

The U.S. government would not back a similar program, said David Murray of the White House Office of National Drug Control Policy in Washington, D.C. He said addiction should be treated as a disease to be cured.

"We do not acquiesce in cancer; we fight it," he said. "To acquiesce in various addictions seems to be a deeply troubling, ethical and governmental hazard."


Benedikt Fischer, an associate professor at the University of Toronto and a member of the Center for Addiction and Mental Health, disagreed.

"I know that from the United States, this often looks like a form of surrendering to addiction," said Fischer, who is also working on the Vancouver heroin project. "But quite the contrary, we see this as a potential way of bringing people" into treatment.

Very little heroin will be at the Vancouver site, and stringent security measures will be taken, Schechter said.

Part of the project is to attract users to a clinical setting where they can get other help to kick their habits and stabilize their lives.
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Do you get the impression that we Canucks are not only going out of our way to annoy the Americans but are actually getting a perverse thrill doing so?
:wink:
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Re: Canadian Clinic to Try Prescribing Heroin

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Do you get the impression that we Canucks are not only going out of our way to annoy the Americans but are actually getting a perverse thrill doing so?
:wink:
Well it's not like the American policy of fighting drug abuse is working. If something doesn't work than you have to try other methods.
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Re: Canadian Clinic to Try Prescribing Heroin

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Cpl Kendall wrote:
Well it's not like the American policy of fighting drug abuse is working. If something doesn't work than you have to try other methods.
I agree--and during my addiction counselor training, I subscribed to the harm reduction approach--i.e. While it's really nice and desirable to give up the addiction for good, that's simply not doable for some people in some circumstances, so you might as well try your best to minimize the harm to themselves and others by doing something else.

I'm definitely going to be keeping a close look on this.
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Post by Illuminatus Primus »

I love how U.S. Gov policy toward social problems is to treat them ideologically; what that prick is stating is precisely counter to scientific medicine: you go with what works and helps the patient. Period.
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Post by Illuminatus Primus »

Even better is this farcical moral flag-waving over, "OMG THEY'RE USING HEROIN!!!!one+shift....we only use every other opiate under the sun in both drug treatment or medical practice, but oh god, not the chemical structure of heroin [makes finger cross]."
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Post by Wicked Pilot »

News flash people, heroin is fucking dangerous. If you screw around with that shit you will lose. For some people who have serious addictions and are just too pathetic to control themselves I could somewhat support drastic measures like this, but in my unprofessional opinion I don't see much good coming from this study.
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Post by Illuminatus Primus »

There's almost no meaningful difference between heroin and morphine or methadone. The only difference is that heroin, or diamorphine, causes more of a euphoria when used. Diamorphine is actually simply an esterified morphine molecule.

This is really nothing much different than was already going on. If you're against this, you should be against methadone treatment.
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Post by RedImperator »

Wicked Pilot wrote:News flash people, heroin is fucking dangerous. If you screw around with that shit you will lose. For some people who have serious addictions and are just too pathetic to control themselves I could somewhat support drastic measures like this, but in my unprofessional opinion I don't see much good coming from this study.
In the 19th century, this was a common treatment for opitate addiction (which reached rates unheard of today, thanks to patent medicines which were basically over the counter liquid morphine). It allowed people to function--sometimes for decades--with their addictions. They treated addiction as a chronic condition--which is is--rather than an acute one that can be cured by prison.
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Post by Pick »

I personally believe if there is a valid medicinal reason for it to be used, it'd be stupid not to. :?

Isn't that the point of medicine?

At least this doesn't apparently cause ye olde "oily gaseous discharge and an inability to control them." :P
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Post by Wicked Pilot »

I have to emphasis again my lack of knowledge in this field, but it strikes me that at some point you need to get someone off the juice if you want to cure them, not just feed them something else indefinately. What's wrong with isolating someone from their addiction until it's completely out of their system? I'd imagine the shakes aren't a fun thing, but can't we just chalf that up to being a temporary punishment for your stupid choices in life?
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Re: Canadian Clinic to Try Prescribing Heroin

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dr. what wrote:Do you get the impression that we Canucks are not only going out of our way to annoy the Americans but are actually getting a perverse thrill doing so? :wink:
Yup, I can't wait to see what those silly Americans will do when we decriminalize marijuana.
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Post by Illuminatus Primus »

You can't do that with severe opiate addiction. Opiates, among other things, suppress your heart rate and blood pressure. Since junkees are practically always somewhat crocked up on opiates, their cardiovascular system adjusts to compensate living in nigh-constant state of medication (opiate addicts need much higher amounts of anesthesia due to this, relative to the average person). As a result, if an opiate addict goes cold turkey, they can often have their blood pressure and heart rate spike rapidly as part of their withdrawal symptoms. Strokes, heart attacks, and other conditions can kill opiate addicts. Opiate addiction is one of those addictions where the withdrawals really can directly kill you.
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Post by Andrew J. »

Wicked Pilot wrote:I have to emphasis again my lack of knowledge in this field, but it strikes me that at some point you need to get someone off the juice if you want to cure them
You'd need to forcibly isolate them for a prolonged period of time. Good luck getting willing participants with that.
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Post by Wicked Pilot »

Andrew J. wrote:You'd need to forcibly isolate them for a prolonged period of time. Good luck getting willing participants with that.
Seeing how these substances are illegal (which is not something I in all cases agree with mind you), jail time would be a good motivator and/or cure.
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Post by Aaron »

Wicked Pilot wrote:
Seeing how these substances are illegal (which is not something I in all cases agree with mind you), jail time would be a good motivator and/or cure.
Actually there is quite easy access to drugs in jail. They may not be able to shoot up heroin, but they can smoke it.
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Post by Wicked Pilot »

Cpl Kendall wrote:Actually there is quite easy access to drugs in jail. They may not be able to shoot up heroin, but they can smoke it.
I'm sure that for the hard core user the supply won't be enough to keep them up at the usual level. Solitary would go even further towards cutting them off. However further discussion would be getting off topic, so let's just operate under the assumption that it is 100% possible to forcibly seperate addicts from their fix, with the question being is it the right/appropiate thing to do.
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Post by Illuminatus Primus »

Why bother? Methadone treatment DOES work, especially from hardcore addicts, it just takes more time and the religious-esque-minded anti-drug crowd goes "DRUGZ! TEH EVILLLL," even though they'd just love to crocked on morphine after surgery, which is only a slower-acting form of heroin anyway.

Besides, as I said before, dealing with an addict like the ones you're talking about, you may very well kill them by making them go cold-turkey.
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Post by tharkûn »

There's almost no meaningful difference between heroin and morphine or methadone. The only difference is that heroin, or diamorphine, causes more of a euphoria when used. Diamorphine is actually simply an esterified morphine molecule
:roll:

The major difference is that heroin can cross the blood/brain barrier ridiciously faster than morphine. This is why heroin is injected - after a couple of minutes it loses its ability to cross the blood/brain faster than morphine. The uptake curve for heroin is essentially a giant friggen spike, for morphine it is closer to a standard bell. Time dosing diacetylmorphine is MUCH harder than standard morphine and far less uniform, this is why medicine prefers morphine even though you need larger quantities of the drug for the same effect - it is way bloody easier to manage delivery rate.

This is really nothing much different than was already going on. If you're against this, you should be against methadone treatment.
The difference is in the rate at which it happens; how fast does it go to the brain, how fast is it eliminated from the body, etc. You can overdose on heroin even when a mass equivalent amount of morphine won't kill you for this reason.

In the 19th century, this was a common treatment for opitate addiction (which reached rates unheard of today, thanks to patent medicines which were basically over the counter liquid morphine). It allowed people to function--sometimes for decades--with their addictions. They treated addiction as a chronic condition--which is is--rather than an acute one that can be cured by prison.
What this study is looking at is if a mixture of heroin and methadone are superior at weaning the addict off opiates, rather than maintaining the addiction for decades. It is quite likely that such an approach will meet similar results as the nicotene patches - gradual decrease in the narcotic administered will lead to a lessoning of withdrawal symptoms and eventually the addict will not be psyiologically dependent on the narcotics.

I beleive the Swiss are also looking into this.
What's wrong with isolating someone from their addiction until it's completely out of their system? I'd imagine the shakes aren't a fun thing, but can't we just chalf that up to being a temporary punishment for your stupid choices in life?
That can be a very short life. Heroin withdrawal is friggen scary, that is why they are given methadone. Even though methadone itself is addictive and plays merry hell on opoid receptors, it is generally thought to be more effective than cold turkey.
Seeing how these substances are illegal (which is not something I in all cases agree with mind you), jail time would be a good motivator and/or cure.
Jail tends not to deal with the pyscological roots of addiction and even in jail going from 500 mg (extremely hardcore heroin junkies, a medicinal dosage would range from .5-2mg for comparison) to nothing is generally frowned upon even in the most hardass jails. Methadone is already in use because it makes withdrawal less torturious.
Actually there is quite easy access to drugs in jail. They may not be able to shoot up heroin, but they can smoke it.
Heroin has a half-life of two minutes in the body, to maintain an addiction without injection takes either lots of heroin or high quality heroin. Why do you think they inject the stuff in the first place? Because getting high in other ways takes more or purer heroin. The costs of maintaining addict heroin levels via smoking is going to be prohibitive for any but the most wealthy of prisoners.
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