Gays and Giving Blood

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Rye
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Post by Rye »

haas mark wrote: See the above. If that's the case, then if clean blood is clean blood, then what does it matter if it comes from a man that has had sex with another man?
Why take the risk? To the blood bank, you're an faceless name that endulges in high risk behaviour. Why should they go out on a limb, even if it doesn't seem fair?

Yes, they want a high volume of blood, but they want it good quality and as fast as possible, since it spoils. So yeah, cutting out donors by apparently unfair generalisations basically amounts to playing the odds for the best product. Don't take it personally.
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Post by haas mark »

Rye wrote:
haas mark wrote: See the above. If that's the case, then if clean blood is clean blood, then what does it matter if it comes from a man that has had sex with another man?
Why take the risk? To the blood bank, you're an faceless name that endulges in high risk behaviour. Why should they go out on a limb, even if it doesn't seem fair?

Yes, they want a high volume of blood, but they want it good quality and as fast as possible, since it spoils. So yeah, cutting out donors by apparently unfair generalisations basically amounts to playing the odds for the best product. Don't take it personally.
I'm not taking it personally; I'm asking why this should be so.
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Post by Justforfun000 »

I don't know......I'll look at these arguments against what I said afterwards, but my first reaction was still a lot of smoke rather then substance.....I have no problem with common sense....I have no problem with SEEEMINGLY bigoted/prejudicial behaviour if it can be backed up with evidence and common sense. But these arguments I'm seeing seem like they are REALLY reaching to try and justify themselves. In any event, I'll read them fresh afterwards.....I just got in the door on a late night of working all weekend and I"m tired.
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Post by haas mark »

Justforfun000 wrote:I have no problem with SEEEMINGLY bigoted/prejudicial behaviour if it can be backed up with evidence and common sense.
It may be a small line between bigotry and idiocy, but this has progressed to the latter.
tharkûn wrote:Public perception comes from which populations are allowed to donate.
What perception is to be had if people don't know?
tharkûn wrote:If you are going to change the exclusions then you need clinical data to allay the fears everyone but the most bigoted morons.
The difference between whether blood is usable is not good enough clinical data?
tharkûn wrote:Because there is leftover fear from when AIDS was GRID and too many people remain ignorant.
And the fact that they are basing something on risk rather than fact is not ignorance?
tharkûn wrote:Virgins are not excluded in the blood bank, the exclusion is men who have sex with men, not men with homosexual orientation.
...You missed the point. I made an example which obviously flew over your head. I said they were no more scared of virgins than those that are sexually active. And yet, despite that my last sexual partner was nearly two years ago and the fact that it was safe discounts the fact that it was with a man, despite my being clean for any sexually transmitted diseases. If I were to try to donate blood next February (I can't until then because of a tattoo) and say that yes, I had had a sexual partner that was male, I would not be allowed to donate my blood based on that fact, despite being clean. Tell me, does that make a lick of sense to you? It sure as hell doesn't to me.
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Post by tharkûn »

What perception is to be had if people don't know?
People would know. Whenever the Red Cross or whomever even meets to discuss the blood exclusions they make the press and slowly whatever they decide filters into the general public. In the case of removing exclusions it would take a matter of days before some donor would notice the 'missing' exclusions, post it on the internet, and then it is only a matter of time before the world knows a change was made.
The difference between whether blood is usable is not good enough clinical data?
The clinical data about whether their blood is usable is not good enough. It is known that the standard clinical tests used to detect HIV, Hepatitis, etc. have a window where they give a false negative. Because of that a certain amount of failure must be assumed. Therefore the blood banks have a vested interest in excluding populations which have higher rates of infection. Unfortunately the MSM population does carry a demonstrably higher risk.
And the fact that they are basing something on risk rather than fact is not ignorance?
It is ignorance, but the goal of the blood bank is to save lives, not be fair. If a significant proportion of the population has perception problems then it must be dealt with or the blood bank fails to serve its purpose.

The most striking example of this is the BSE exclusion. In the US about 5% of potential blood donors are excluded because they have spent 6 months in the UK. To the best of my knowledge there is not a single instance of BSE transmission through the blood supply. To the best of my knowledge the percentage of infected Britons is ludicriously low. To the best of my knowledge removing the BSE exclusion would not result in a single person being infected.

They keep the BSE exclusions in place, in large part, because they don't want the public to be scared of catching mad cow disease from the blood supply.
I made an example which obviously flew over your head. I said they were no more scared of virgins than those that are sexually active.
Why would they be?
And yet, despite that my last sexual partner was nearly two years ago and the fact that it was safe discounts the fact that it was with a man, despite my being clean for any sexually transmitted diseases. If I were to try to donate blood next February (I can't until then because of a tattoo) and say that yes, I had had a sexual partner that was male, I would not be allowed to donate my blood based on that fact, despite being clean. Tell me, does that make a lick of sense to you? It sure as hell doesn't to me.
Yes. Including people like yourself results in a 60% risk increase according to the data already cited. That may be because people lie, because people misanswer questions about "safe", "clean", and "sex" due to different definitions, or something else entirely. Right now the data says that allowing MSM who have not had male-male intercourse in the last year to donate increases the risk.

It is possible that better exclusion, say no MSM intercourse for 12 months, barrier use during the entire relationship, and seronegativity tests 6 months after the last act of sex would not show an apreciable increase in risk. To date no one has done that work - so the rules stay the same until someone gets actual data that includes the effect of: people lying, people misusing condems, people testing too soon after the last act of sex, etc. It is possible that even with all the error sources the risk is negligable and the blood bank faces only a perception issue. If that is the case then good clinical data should allay the perception issues (given sufficient time) of all but the most bigoted.
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Post by haas mark »

tharkûn wrote:People would know. Whenever the Red Cross or whomever even meets to discuss the blood exclusions they make the press and slowly whatever they decide filters into the general public. In the case of removing exclusions it would take a matter of days before some donor would notice the 'missing' exclusions, post it on the internet, and then it is only a matter of time before the world knows a change was made.
Point, but you're missing the overall thing, really.
The clinical data about whether their blood is usable is not good enough. It is known that the standard clinical tests used to detect HIV, Hepatitis, etc. have a window where they give a false negative.
I know that, but there is also a period after which it can be determined to not be so. So even after that window of incubation, there is somethig that I remember from the United Blood Services pamphlet - if you're a man who has had sex with a man, period, they won't take your blood.
Because of that a certain amount of failure must be assumed. Therefore the blood banks have a vested interest in excluding populations which have higher rates of infection. Unfortunately the MSM population does carry a demonstrably higher risk.
Per capita.
It is ignorance,
SOmething we agree on, then.
but the goal of the blood bank is to save lives, not be fair.
And exactly what surplus of donated blood do we have?
If a significant proportion of the population has perception problems then it must be dealt with or the blood bank fails to serve its purpose.
Why does perception even matter?
The most striking example of this is the BSE exclusion.
BSE? What is that?
In the US about 5% of potential blood donors are excluded because they have spent 6 months in the UK. To the best of my knowledge there is not a single instance of BSE transmission through the blood supply. To the best of my knowledge the percentage of infected Britons is ludicriously low. To the best of my knowledge removing the BSE exclusion would not result in a single person being infected.
Be that as it may, and I agree with you here, the fact of the matter is not about low risk diseases or anything else so much as determining whether blood is clean. There are some, yes, that have a period where they may be incubating still. But take, for example, if two men have been exclusive partners for over a year, and have been clean since day one. If they've only had sex with each other, and have not participated in any actions that may infect them, they're still not allowed to donate blood.
Why would they be?
I wasn't saying they would - or should - be, just making a point. Sexually active people are more likely to acquire some sexually transmitted disease that can be passed through blood. By all logic, you shouldn't have anyone donate blood but virgins that have never used a needle or gotten something that would affect their blood.
Yes. Including people like yourself results in a 60% risk increase according to the data already cited.
What about the other 40%? Second, I've been tested since then (the last time was over a year since my last sexual partner) and came up clean.
That may be because people lie, because people misanswer questions about "safe", "clean", and "sex" due to different definitions, or something else entirely.
And what about just lying about their sexual partners because of the fact they know they're clean?
Right now the data says that allowing MSM who have not had male-male intercourse in the last year to donate increases the risk.
How does it increase risk if they haven't had sex? That makes absolutely no sense, whatsoever!
It is possible that better exclusion, say no MSM intercourse for 12 months, barrier use during the entire relationship, and seronegativity tests 6 months after the last act of sex would not show an apreciable increase in risk.
What about listing number of sexual partners? I mean, hell, what about the sexually promiscuous heterosexual people out there? They're at a great risk for transmitting diseases, too.
To date no one has done that work - so the rules stay the same until someone gets actual data that includes the effect of: people lying, people misusing condems, people testing too soon after the last act of sex, etc.
I say again that by all logic, it may as well only be virgins allowed to donate blood.
It is possible that even with all the error sources the risk is negligable and the blood bank faces only a perception issue. If that is the case then good clinical data should allay the perception issues (given sufficient time) of all but the most bigoted.
Again, why does perception matter? I've asked this several times in this thread and you've yet to answer that.

Second, if clean blood is clean blood, then why does anything else matter to begin with? You'va also yet to answer this question!
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Post by tharkûn »

I know that, but there is also a period after which it can be determined to not be so. So even after that window of incubation, there is somethig that I remember from the United Blood Services pamphlet - if you're a man who has had sex with a man, period, they won't take your blood.
The numbers back them up. If there is a better set of exclusions than blanket MSM all that needs to be done is demonstrate their effectiveness and most haematologists will back the change.
And exactly what surplus of donated blood do we have?
Enough to exclude upwards of 5% of the donor population on BSE grounds. If you are worried about a blood shortage the BSE exclusions would be the first place to make changes, there is no demonstrated risk to including them and you get many more potential donors for relaxing them. Again there is a three way trade off here: blood safety, risk perception, and availible donors. While it would be nice to increase the latter, it is a hard sell when you decrease the former.
Why does perception even matter?
When you have a child in a car accident who was exsaunginating do you want her doctor to have to dick around with parents afraid of the blood supply (either convincing them of the safety or going through the hoops to override parental consent)? No medical professional I know thinks that is a good thing. Likewise when you have an urgent, but not immediately life threatening condition and you require blood transfusions, do you want to have doctor's forced to wait until they can suck dry a familial donor? There are many ways in which a suspect blood supply hurts people, and not just those who are ignorant. These are sufficiently worrisome that blood banks would rather have overly broad exclusions than have these issues.

The long and the short of it is a suspect blood blank, legitimate suspiscions or not, is bad for public health.
BSE? What is that?
Bovine spongiform encephalopathy, aka mad cow disease.
But take, for example, if two men have been exclusive partners for over a year, and have been clean since day one. If they've only had sex with each other, and have not participated in any actions that may infect them, they're still not allowed to donate blood.
The problem comes in that "exclusive" requires on partner to take the other at his word. There will be a certain percentage of "exclusive" couples which aren't in fact truly "exclusive", those couples where one partner is lying will increase the risk factor. Wether or not that is enough to warrant a blanket exclusion, I don't know, but until there is clinical evidence you stay with the exclusions that have been working.
Sexually active people are more likely to acquire some sexually transmitted disease that can be passed through blood. By all logic, you shouldn't have anyone donate blood but virgins that have never used a needle or gotten something that would affect their blood.
It is a tradeoff. Safe blood, low risk perception, and high numbers of donors. Excluding the MSM population, at most 6 odd % of population in Britain (in reality it will be lower as some of those individuals are excluded on other grounds as well, i.e. they've had an organ transplant as well as the fact that the 6% likely includes non-MSM (bi)homosexuals). The blood bank can afford to exclude 6% of the population, it cannot afford to exclude 80-90% of the population.
What about the other 40%? Second, I've been tested since then (the last time was over a year since my last sexual partner) and came up clean.
You aren't getting the numbers right. According the literature including people like yourself results in a 60% increase in risk - in other words if right now 1.2 persons per annum are infected by blood transfusion, then 1.9 will be expected to be infected by including persons like yourself (MSM, but no intercourse within the last 12 months). Removing the entire MSM exclusion results in a 500% increase in risk.

This is a quality control game, and the blood supply wants to be in excess of 99.9999% safe.
And what about just lying about their sexual partners because of the fact they know they're clean?
Nobody knows if they are clean, depending on the test and risks you take you might be 99% sure you are clean but it is impossible to be certain. The only person I'm going to trust make decisions about who is "clean" is going to have a doctorate in haematology.

Yes there are those who know they are a much smaller risk to the blood supply than most of the people they get categorized with. The problem is if it is okay for one person to say, but I'm not as risky as everyone else, how do we keep those who really are risky from making a wrong self-diagnosis. The exclusions are made they way they are because we DON'T want people having to make complicated risk analysis and while you may trust your partner, the rest of don't know him and would rather not rely on his honesty.
How does it increase risk if they haven't had sex? That makes absolutely no sense, whatsoever!
There are different ways of testing the blood, when you use a more sensitive (but extremely cost/time prohibitive) test you can get a lower limit at the number of false positives you will get with the standard test. When using this more sensistive test in clinical studies it was found that MSM - no intercourse in 12 months carried a 60% higher risk. That could be due to extremely long term incubation, compromised antibody function, lying about sexual history, or something else completely. Frankly what is causing it is irrelevent to the blood supply, what matters is that the risk exists and must be dealt with.

Most countries use ELISA to test the blood, it is quick, cheap, and easy. It also requires at least two weeks and possibly 6 months for seroconversion to set in. PCR measures viral load itself, not antibodies, and can detect HIV (and most any other viral disease) when other tests fail. The blood banks cannot afford to PCR every sample that comes through, but you can do clinical trials with it. From those we know that MSM- no intercourse for 12 months carries a 60% higher risk.
What about listing number of sexual partners? I mean, hell, what about the sexually promiscuous heterosexual people out there? They're at a great risk for transmitting diseases, too.
The literature is in extremely good agreement that people lie about that number more than any other sex statistic (think about it how can the average number of male partners dwarf that of females?). Given that in long term relationships it is the total number of partners both have had that matters, it becomes extremely problematic. There should be an exclusion, but it is doubtful that it will be terribly effective.
I say again that by all logic, it may as well only be virgins allowed to donate blood.
It is a tradeoff. Eventually you hit a law of diminishing returns. Right now the experts deem the trade off of a MSM - no intercourse in the last 12 months to not be a good one in terms of risk increased vs donor pool increased.
Second, if clean blood is clean blood, then why does anything else matter to begin with? You'va also yet to answer this question!
We don't know what is clean blood. Even when you use PCR or bDNA you still have a number of false negatives. When can dramaticly increase the cleanliness of the blood, but we can't make it entirely clean. Due to the fact that we can't spot clean blood, we exclude those most likely not to have it. It comes down to probability and if there is a .0001% chance of bloodborn infection, they will exclude even several percent of the population.
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