Native Australians were driven of cliffs, shot and generally subjected to what can only be described as genocide, disease was only part of it. Native Americans were close behind, ethnically cleansed would be a good description for their treatment, their remnants, after being herded onto 'reservations' like cattle, were but a shadow of the nations they were.Lord of the Abyss wrote:It was far easier in real-world Australia than it would be in a North/South America that wasn't decimated by European plagues. The native Australians were decimated by plague as the American natives were. Places like Africa, Asia, India that WEREN'T decimated generally didn't suffer the genocide-and-replace treatment.Stuart Mackey wrote:They would also be equally happy wipe them out if it suited their purposes, as happened in Australia to the Aborigines there. Their only hope would be able to fight them to a stand still in some way, as in NZ, and gain a peace of some sort.Lord of the Abyss wrote: Qualms, no; they'd have cheerfully wiped the planet clean of everyone but themselves. But judging from history, unless the population is small they weren't likely to bother, and would subjugate them instead. They would have forcibly converted them to Christianity.
Even if one assumes they are resistant to human disease, they must be culturally and technologically up to play with human, particularly western, nations, and the history of the Inca shows the necessity of technology and India and Asia the necessity of a degree of political and cultural cohesion. The only ones who were able to resist were the Japanese, and they did so very well.