I don't know whether the cut scenes are cannon, but for this I'd expect kinetic barriers to be able to interact with everything down to an atomic level, since they can act as atmosphere shields. So as people have said above, any weapon that would have a kinetic component, even if it's a particle pulse weapon, should be deflected, at least in part, by the barriers.
So given we see Particle beam weapons pass right through the barriers (which they shouldn't), that must mean that there must be something in play similar to what Ted C mentioned, that being the barriers have some form of sensor system to them which detects something coming towards the ship and puts the barrier between the ship and the incoming threat, with anything above a certain velocity not being detected...
Ugh makes my head hurt, the very idea that the barriers can somehow detect a 20KG projectile travelling at 0.013c (or whatever) and be able to deflect it, when the main sensors can't detect a ships mass that's hiding it's thermal emissions is rediculous and laughable.
But we never see a large object hit barriers. We know that infantry level barriers can deflect "grain of sand" size projectiles, but at the same time a ship can generate barriers as I've said above. The tech is too varied within the setting from a game play, cut scene and codex point of view, hence me opening with "They work as advertised".From what little I remember of the Mass Effect codex, the way that shields work is that they generate a really sharp gravitational field gradient at a certain distance away from the emitter. Smaller objects that hit that gradient experience a sharp change in mass at the front, and the resulting change in momentum deflects sufficiently small, fast-moving objects. Larger objects can pass through without being deflected for whatever reason.