In terms of fuel, both fission and fusion fuel is refined from prevalent materials (water or uranium ore), so let's assume fuel for both is trivial.
In terms of cost, I'll be generous to fusion and say that in the future we may be able to use LK-99 or some other cool tech to make fission and fusion capital costs and operating costs per MW identical. Given the immense increased complexity of fusion reactors, I think this is quite the concession to fusion!
The common assumptions is that fusion would have advantages when it comes to radioactive safety or nuclear waste. The risk of nuclear meltdown with fission is remote with literally a handful of accidents in older plants caused by human error. Perhaps that is enough to make fission politically infeasible, but I think this is irrational. Though fusion requires power to maintain the reaction, and thus a run-away reaction is not a risk, I can certainly see how human error with a highly sophisticated facility that requires radioactive fuel (tritium) can lead to environmental disasters.
When it comes to nuclear waste, I don't see why fusion would be waste free! The most accessible type of fusion is D-T fusion which generates significant neutron flux. Again, the tritium fuel is radioactive and we're going to end up with a neutron-embrittled and radioactive reactor casing that we need to periodically replace, see discussions about DEMO reactor https://iopscience.iop.org/article/10.1 ... 326/ac62f7
Some may say that we'll get to aneutronic fusion, and that'd be awesome, but my guess is that there will still be unwanted side fusion reactions that generate those pesky neutrons and lead to radioactive waste.4.2. Fusion versus GEN-IV fission
Recent calculations [15] considered activation waste volumes holistically when comparing waste from fusion to GEN IV fission. Under the current UK regulatory waste classifications system, they found that the European sodium-cooled fast reactor (ESFR) has a lower fraction of ILW or HLW in the structural components (i.e. ignoring fuel) compared to the latest concepts for the European DEMO. Considering DEMO's much larger size (the equivalent containment vessel and interior of DEMO is massive and could be as much as ten times as large as ESBWR—see figure 3). This suggests a significantly greater waste burden from fusion in comparison to fission reactors developed on the same timescales. DEMO may produce as much as 10 000 t of solid waste from in-vessel components alone [16], compared to around only 2000 t from ESFR [15] plus an estimated 300 t of spent fuel produced during ESFR's lifetime [17] resulting in ∼2500 t of waste (HLW, ILW). While ESFR produces four times less waste, it will generate much longer-lived actinide waste.
Meanwhile, fission of course also generates nuclear waste. However, fission is a mature technology, now with 4th generation plants being built with decreased cost and more safety advances, and countries do have experience in dealing with the nuclear waste. Even if fusion and fission generate the same amount of nuclear waste that requires storage (note the above reference suggests fusion generates more waste), fusion has the same political cost of convincing people that nuclear waste can be managed safely.
So, even with these generous assumptions to fusion, fission still looks like a better deal. What am I missing? If people are saying fusion energy can solve all our problems, what can it truly do that fission cannot? If we are not willing to ramp up fission energy production now, why are we assuming that we would be willing to ramp up fusion once a commercially viable fusion plant is available? And even if we could solve the political problems, why would we bother with increased complexity of fusion over more proven fission for terrestrial power production?
As an aside, fusion engines/generators on spaceships would be sick! There you'd get the full benefit from the increased energy density and higher temperatures from fusion.